This medication is used in the treatment of high blood pressure. It is effective when used alone or when combined with other high blood pressure medications. It may also be used with other medications in the treatment of heart failure, and may be given within 24 hours of a heart attack to improve chances of survival. Lisinopril (Zestril) is a type of drug called an ACE inhibitor. It works by reducing production of a substance that increases salt and water retention in your body.
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