24 Hour
Metformin
Tablets
Chemical Name: METFORMIN
(met-FOR-min)
Common
Metformin
uses
This medicine is a biguanide-type
medicine used along with a
diet and exercise program to
control high blood sugar in
patients with type 2 diabetes.
This medicine works by helping
restore your body's proper
response to the insulin you
naturally produce, and by
decreasing the amount of sugar
that your liver makes and that
your stomach/intestines
absorb. Controlling high blood
sugar helps prevent heart
disease, strokes, kidney
disease, blindness,
circulation problems, and
sexual function problems.
Before using
Metformin
WARNING: Metformin can rarely
cause a condition called
lactic acidosis, which can be
fatal. Seek immediate medical
attention if you develop any
of the following symptoms of
lactic acidosis: unusual
tiredness (fatigue) or severe
drowsiness, cold skin, muscle
pain, breathing trouble or
rapid breathing, or unusually
slow or irregular heartbeat.
Lactic acidosis is more likely
to occur in patients who have
heart failure, kidney or liver
problems, excessive alcohol
use, a lack of body fluids
(dehydration), x-ray or
scanning procedures that
require an injectable
iodinated contrast drug,
surgery, a serious infection,
heart attack, or stroke, Also
at higher risk are the
elderly, especially if you are
over 80 years of age and have
not had kidney and liver
tests. Some medicines or
medical conditions may
interact with this medicine.
INFORM YOUR DOCTOR OR
PHARMACIST of all prescription
and over-the-counter medicine
that you are taking.
ADDITIONAL MONITORING OF YOUR
DOSE OR CONDITION may be
needed if you are taking other
diabetes drugs (e.g.,
glyburide, insulin), "water
pills" (diuretics such as
hydrochlorothiazide,
furosemide), cimetidine, birth
control pills, estrogens,
corticosteroids (e.g.,
prednisone), niacin, phenytoin,
decongestants, high blood
pressure drugs (beta-blockers
such as propranolol, calcium
channel blockers such as
nifedipine, ACE inhibitors
such as captopril),
phenothiazines (e.g.,
chlorpromazine), isoniazid,
thyroid drugs, clomiphene,
fenugreek, or ginseng. USE OF
THIS MEDICINE IS NOT
RECOMMENDED if you have a
history of kidney disease,
liver disease, congestive
heart failure, metabolic
acidosis (e.g., diabetic
ketoacidosis), recent heart
attack, recent stroke, serious
infection, or dehydration.
Inform your doctor of any
other medical conditions
including blood problems
(e.g., anemia, vitamin B-12
deficiency), scheduled
upcoming surgery, scheduled
upcoming x-ray or scanning
procedures, alcohol use, any
allergies, pregnancy, or
breast-feeding. If you are
scheduled to undergo any x-ray
or scanning procedure using
injectable iodinated contrast
material, be sure to inform
your doctor that you are
taking this medicine. You will
need to temporarily stop this
medicine around the time of
your procedure. Consult your
doctor for further
instructions. Do not start or
stop any medicine without
doctor or pharmacist approval.
Contact your doctor or
pharmacist if you have any
questions or concerns about
taking this medicine.
Metformin
Directions
Follow the directions for
using this medicine provided
by your doctor. SWALLOW WHOLE.
Do not break, crush, or chew
before swallowing. TAKE THIS
MEDICINE with food. DRINK
PLENTY OF FLUIDS while taking
this medicine. CONTINUE TO
TAKE THIS MEDICINE even if you
feel well. Do not miss any
doses. Use this medication
regularly in order to get the
most benefit from it. To help
you remember, use it at the
same time each day. This
medicine may come with a
patient information leaflet.
Read it carefully. Ask your
doctor, nurse, or pharmacist
any questions that you may
have about this medicine.
STORE THIS MEDICINE at room
temperature between 68 and 77
degrees F (20 and 25 degrees
C), away from light and
moisture. Brief storage
between 59 and 86 degrees F
(15 and 30 degrees C) is
permitted. Do not store in the
bathroom. Keep all medicines
away from children and pets.
IF YOU MISS A DOSE OF THIS
MEDICINE, take it as soon as
possible. If it is almost time
for your next dose, skip the
missed dose and go back to
your regular dosing schedule.
DO NOT take 2 doses at once.
Metformin
Cautions
FOLLOW THE DIETARY PLAN
provided by your doctor. KEEP
ALL DOCTOR AND LABORATORY
APPOINTMENTS (e.g., liver and
kidney function tests, fasting
blood glucose, glycosylated
hemoglobin, complete blood
counts) while you are using
this medicine. Regularly check
your blood or urine sugar as
directed by your doctor.
BEFORE YOU HAVE ANY MEDICAL OR
DENTAL TREATMENTS, EMERGENCY
CARE, LABORATORY TESTS, OR
SURGERY, tell the doctor or
dentist that you are using
this medicine. During times of
stress such as fever,
infection, injury or surgery
it may be more difficult to
control your blood sugar.
Consult your doctor, as a
change in your medication may
be required. LIMIT ALCOHOL
INTAKE while using this
medicine. BEFORE YOU BEGIN
TAKING ANY NEW MEDICINE,
either prescription or
over-the-counter, check with
your doctor or pharmacist.
Caution should be used in the
elderly since they may be more
sensitive to the effects of
this drug. FOR WOMEN: This
medicine can cause changes in
the menstrual cycle (promote
ovulation) in women with
certain fertility problems,
therefore increasing the risk
of becoming pregnant. Consult
your doctor or pharmacist
about the use of reliable
birth control while using this
medicine. IF YOU PLAN ON
BECOMING PREGNANT, discuss
with your doctor the benefits
and risks of using this
medicine during pregnancy. IT
IS UNKNOWN IF THIS MEDICINE IS
EXCRETED in breast milk. DO
NOT BREAST-FEED while taking
this medicine.
Possible
Metformin
side effects
Also see the BEFORE USING THIS
MEDICINE section. SIDE
EFFECTS, that may go away
during treatment, include
metallic taste in mouth,
nausea, stomach upset, or
diarrhea. If they continue or
are bothersome, check with
your doctor. If stomach
symptoms recur later (after
you are on the same dose for
several days or weeks), tell
your doctor immediately. A
late recurrence of stomach
symptoms may be due to a
serious medical condition
(lactic acidosis). You may
notice that part of the
original tablet is passed into
your stool. This is normal and
there is no cause for concern.
This medicine usually does not
cause low blood sugar
(hypoglycemia), but this
effect may occur if you do not
consume enough calories (from
food, juices, fruit, etc.).
The symptoms include chills,
cold sweat, dizziness,
drowsiness, shaking, rapid
heartbeat, weakness, headache,
fainting, tingling of the
hands or feet, or hunger. It
is a good habit to carry
glucose tablets or gel to
treat low blood sugar. If you
are in a situation where you
don't have these reliable
forms of glucose, eat a quick
source of sugar such as table
sugar, honey, or candy, or
drink a glass of orange juice
or non-diet soda to quickly
raise your blood sugar level.
Tell your doctor immediately
about the reaction. To help
prevent hypoglycemia, eat
meals on a regular schedule
and do not skip meals.
Symptoms of high blood sugar
(hyperglycemia) include
thirst, increased urination,
confusion, drowsiness,
flushing, rapid breathing, or
fruity breath odor. If these
symptoms occur, tell your
doctor immediately. Your
medication dosage may need to
be increased. IF YOU
EXPERIENCE difficulty
breathing; tightness of chest;
swelling of eyelids, face, or
lips; or if you develop a rash
or hives, tell your doctor
immediately. Do not take any
more doses of this medicine
unless your doctor tells you
to do so. If you notice other
effects not listed above,
contact your doctor, nurse, or
pharmacist.
Drug interactions
Drug interactions can result
in unwanted side effects or
prevent a medicine from doing
its job. Use our drug
interaction checker to find
out if your medicines interact
with each other.
Check drug interactions
If you take too much
Metformin
If overdose is suspected,
contact your local poison
control center or emergency
room immediately. Symptoms of
overdose may include rapid or
trouble breathing, severe
drowsiness, and slow or
irregular heartbeat.
Additional
Metformin
information
This medicine is not a
substitute for proper diet and
regular exercise. It is
recommended you attend a
diabetes education program to
better understand diabetes,
prevention of complications,
and all the important aspects
of its treatment. These
include meals/diet, exercise,
weight loss, personal hygiene,
medicine and blood glucose
monitoring, and the need for
regular eye, foot, and medical
exams. Follow your doctor's
instructions carefully. DO NOT
SHARE THIS MEDICINE with
others for whom it was not
prescribed. KEEP THIS MEDICINE
out of the reach of children
and pets. IF USING THIS
MEDICINE FOR AN EXTENDED
PERIOD OF TIME, obtain refills
before your supply runs out.
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