Miscellaneous
Chemical Name: ADVAIR FLUTICASONE (flew-TICK-uh-sone)
and SALMETEROL (sal-MET-er-all)
Common uses of Advair
This product is a combination "controller"
medicine for long-term treatment to prevent
or decrease the symptoms of asthma and
chronic lung diseases such as emphysema,
bronchitis, or COPD. It works to open the
airways of the lungs in two ways (decreasing
bronchiolar swelling and causing muscle
relaxation). It may also be used to treat
other breathing conditions as determined by
your doctor. This medicine does not work
immediately and should not be used for acute
asthma attacks. Use other "quick-relief"
medicines/inhalers for sudden shortness of
breath or asthma attacks.
Before using Advair
WARNING: Salmeterol may rarely be associated
with serious asthma attacks (potentially
fatal). African-American patients and
patients prescribed salmeterol when their
asthma condition is worsening may have an
increased risk for this event. If you find
that your fast-acting inhaler is not working
as well or if you need to use it more often
than usual, such as using 4 or more puffs
daily or using more than 1 inhaler every 8
weeks, tell your doctor or pharmacist
promptly. This may be a sign of worsening
asthma which is a serious condition. DO NOT
SUDDENLY STOP using this medicine. Doing so
may cause your breathing condition to get
worse. Discuss with your doctor the benefits
and risks of using this medicine. Some
medicines or medical conditions may interact
with this medicine. INFORM YOUR DOCTOR OR
PHARMACIST of all prescription and
over-the-counter medicine that you are
taking. ADDITIONAL MONITORING OF YOUR DOSE
OR CONDITION may be needed if you are also
taking other asthma medicines (e.g.,
quick-relief inhalers), oral corticosteroids
(e.g., dexamethasone, prednisone),
beta-blockers (e.g., metoprolol, propranolol),
MAO inhibitors (e.g., furazolidone,
linezolid, moclobemide, phenelzine,
procarbazine, selegiline, isocarboxazid,
tranylcypromine), tricyclic antidepressants
(e.g., amitriptyline, nortriptyline), "water
pills" (diuretics such as furosemide,
hydrochlorothiazide), HIV protease
inhibitors (e.g., ritonavir, lopinavir),
azole antifungals (e.g., itraconazole,
ketoconazole), "adrenaline-like" stimulants
(e.g., pseudoephedrine or ephedra). Use of
this inhaler within 2 weeks after stopping
MAO inhibitors or tricyclic antidepressants
is not recommended, since these medicines
may increase the serious side effects of
salmeterol. DO NOT START OR STOP any
medicine without doctor or pharmacist
approval. Inform your doctor of any other
medical conditions including heart disease
(angina, arrhythmias), liver problems,
diabetes, high blood pressure, low potassium
levels (hypokalemia), eye problems (e.g.,
cataracts, glaucoma), depression, recent
infection, seizures, thyroid problems
(hyperthyroid or hypothyroid), any
allergies, pregnancy, or breast-feeding. USE
OF THIS MEDICINE IS NOT RECOMMENDED if you
have a history of irregular/fast heartbeat
(cardiac tachyarrhythmias), untreated lung
infections (bacterial, fungal, or
tuberculosis), or certain lung diseases (bronchiectasis).
Contact your doctor or pharmacist if you
have any questions or concerns about taking
this medicine.
Advair Directions
Follow the directions for using this
medicine provided by your doctor. This
medicine comes with a patient information
leaflet. Read it carefully. Refer to the
illustrated directions provided for
instruction on the correct use of this
device. Ask your doctor, nurse, or
pharmacist any questions that you may have
about this medicine. Always activate and use
this device in a level, horizontal position.
Do not breathe into the inhaler. Do not use
a spacer. Your dose is based on your
condition and response to treatment. Gargle
and rinse your mouth after using this
medicine to help prevent dryness, relieve
throat irritation, and to prevent mouth
infections (e.g., thrush). Do not swallow
the rinse solution. If you have been using a
"quick-relief" beta agonist inhaler (such as
salbutamol/albuterol) on a regular daily
schedule, you must discontinue this schedule
and only use it "as needed" for acute asthma
attacks. Consult your doctor. Do not take
the inhaler apart or wash the mouthpiece of
the inhaler. STORE THIS MEDICINE at room
temperature as directed on the package, away
from heat, moisture, or light. Keep the
inhaler dry at all times. CONTINUE TO USE
THIS MEDICINE even if you feel well. Do not
miss any doses. IF YOU MISS A DOSE OF THIS
MEDICINE, use it as soon as possible. If it
is almost time for your next dose, skip the
missed dose and go back to your regular
dosing schedule. Do NOT use 2 doses at once.
Advair Cautions
DO
NOT STOP USING THIS MEDICINE without first
checking with your doctor. Some conditions
may become worse when the medicine is
suddenly stopped. Your dose may need to be
gradually decreased. DO NOT EXCEED THE
RECOMMENDED DOSE or use this medicine more
often than prescribed without checking with
your doctor. Doing so would decrease the
effectiveness of the medicine and increase
the risk of side effects. THIS MEDICINE MAY
CAUSE DIZZINESS. DO NOT DRIVE, OPERATE
MACHINERY, OR DO ANYTHING ELSE THAT COULD BE
DANGEROUS until you know how you react to
this medicine. Using this medicine alone,
with other medicines, or with alcohol may
lessen your ability to drive or to perform
other potentially dangerous tasks. Limit
alcoholic beverages. BEFORE YOU BEGIN TAKING
ANY NEW MEDICINE, either prescription or
over-the-counter, check with your doctor or
pharmacist. Check the labels on all your
medicines (e.g., cough-and-cold products,
diet aids) because they may contain
ingredients that could increase your heart
rate and blood pressure. Ask your pharmacist
about the safe use of those products. If you
have switched from an oral corticosteroid
(e.g., prednisone tablets) to this inhaler
within the past 12 months, or if you have
been using this product in higher-than-usual
doses and suddenly stop using it, your body
may not produce enough natural steroids. You
may need to start taking additional
corticosteroids, especially if your body is
stressed due to a major infection, surgery,
or injury. Consult your doctor or pharmacist
for more details, and inform them that you
use (or have used) any type of
corticosteroid. Carry a warning card stating
that you may need supplemental
corticosteroids (e.g., prednisone) during
stress periods (such as trauma or major
surgery). Contact your doctor if you
experience any symptoms of low steroid
levels including unusual weakness, weight
loss, fainting, or dizziness. Caution is
advised when using this medicine in the
elderly because they may be more sensitive
to the effects of the medicine, especially
the effects on the heart (cardiovascular).
Caution is advised when using this medicine
in children. Though it is very unlikely to
occur with inhaled steroids (fluticasone),
this medicine may decrease a child's growth
rate, but not necessarily their final adult
height. Though it is very unlikely with
inhaled steroid use, children using this
medicine might be prone to serious cases of
common infections, such as chickenpox or
measles. Avoid exposing the child to such
diseases. Consult the doctor or pharmacist
for more details. FOR WOMEN: IF YOU PLAN ON
BECOMING PREGNANT, discuss with your doctor
the benefits and risks of using this
medicine during pregnancy. ONE OF THE
MEDICINES IN THIS PRODUCT (SALMETEROL) IS
EXCRETED in breast milk; it is unknown if
the other medicine (fluticasone) passes into
breast milk. DO NOT BREAST-FEED while using
this medicine.
Possible Advair side effects
SIDE EFFECTS that may occur while taking
this medicine include hoarseness (dysphonia),
throat irritation, headache, cough, or dry
mouth or throat. If they continue or are
bothersome, check with your doctor. CHECK
WITH YOUR DOCTOR IMMEDIATELY if you
experience white patches on tongue or mouth,
or if your mouth/tongue becomes swollen and
painful. CONTACT YOUR DOCTOR IMMEDIATELY if
you experience any of the following unlikely
but serious side effects: weight gain,
vision changes, trouble sleeping, tremors,
seizures, severe muscle weakness or
cramping, fast/irregular heartbeat, numbness
or tingling in hands or feet, chest pain, or
worsening of asthma symptoms (e.g.,
increased difficulty breathing, wheezing,
coughing). AN ALLERGIC REACTION to this
medicine is unlikely but seek immediate
medical attention if it occurs. Symptoms of
an allergic reaction include rash, itching,
swelling, dizziness, or trouble breathing.
Rarely, your wheezing might actually
increase immediately after using this
medicine (paradoxical bronchospasm). If this
occurs, use your "quick-relief" inhaler
(such as albuterol). Seek immediate medical
attention if your breathing does not improve
at that time. If you notice other effects
not listed above, contact your doctor,
nurse, or pharmacist.
Drug interactions
Drug interactions can result in unwanted
side effects or prevent a medicine from
doing its job. Use our drug interaction
checker to find out if your medicines
interact with each other.
Check drug interactions
If you take too much Advair
If
overdose is suspected, contact your local
poison control center or emergency room
immediately. Symptoms of overdose may
include seizures, chest pain, unusually
fast/irregular heartbeat, severe muscle
weakness, muscle cramping, and fainting.
Additional Advair information
Carry an identification card at all times
that states you are taking this medicine. IT
IS IMPORTANT that you keep all doctor and
laboratory appointments while you are using
this medicine. Laboratory and/or medical
tests (e.g., IOP, children's rate of growth)
should be performed periodically to monitor
your progress or check for side effects.
Consult your doctor for more information.
Learn to use a peak flow meter, use it
daily, and promptly report worsening asthma
(such as readings in the yellow or red range
or increased use of quick-relief inhalers).
Try to avoid irritants that may trigger an
asthma attack such as smoke, pollen, pet
dander, dust, or molds. DO NOT SHARE THIS
MEDICINE with others for whom it was not
prescribed. KEEP THIS MEDICINE out of the
reach of children and pets. IF USING THIS
MEDICINE FOR AN EXTENDED PERIOD OF TIME,
obtain refills before your supply runs out.
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